The verse Acts 4:27 from the King James Version of the Bible reads, "For of a truth against thy holy child Jesus, whom thou hast anointed, both Herod, and Pontius Pilate, with the Gentiles, and the people of Israel, were gathered together."

This verse comes from the book of Acts in the New Testament and is part of a larger passage that discusses the early Christian church's persecution and the believers' prayer for courage in the face of opposition. This verse specifically refers to the conspiracy against Jesus by Herod, Pontius Pilate, the Gentiles, and the people of Israel.

In this verse, there are several themes and significant symbolism that can be explored. One of the prominent themes is the idea of persecution. The early Christians faced intense persecution for their faith, and this verse highlights the collaborative effort of both Jewish and Roman authorities in opposing Jesus and his followers. This theme of persecution is a significant aspect of the Christian faith, as Jesus himself was persecuted and crucified for his teachings.

Another important theme in this verse is the recognition of Jesus as the "holy child" who was anointed by God. This highlights the divine nature of Jesus and emphasizes the belief in his role as the Messiah. The phrase "holy child" carries a sense of purity and innocence, underscoring the injustice of his persecution and execution.

The verse also serves as a reminder of the sovereignty of God. Despite the collaboration of powerful individuals and groups against Jesus, the overarching plan and purpose of God prevail. The use of the phrase "gathered together" conveys the idea of a unified opposition, but ultimately, it underscores the divine sovereignty and control over all events.

Furthermore, the reference to Herod and Pontius Pilate, as well as the Gentiles and the people of Israel, serves as a representation of the broader spectrum of humanity. This collaboration of diverse groups in opposing Jesus symbolizes the universal rejection of Christ and his message, extending beyond geographical and cultural boundaries.

Symbolically, the verse also points to the concept of God's redemptive plan for humanity. Despite the opposition and persecution faced by Jesus and his followers, the ultimate outcome is one of redemption and salvation. The collaboration of these various groups in executing Jesus ultimately served to fulfill God's plan for the atonement of sin and the reconciliation of humanity to himself.

In its broader context, this verse also serves as a poignant reminder of the ongoing struggles and challenges faced by Christians throughout history. It underscores the reality of persecution and the need for steadfast faith and reliance on God's sovereignty in the face of adversity.

In conclusion, Acts 4:27 from the King James Version of the Bible contains deep and significant meaning with themes of persecution, the sovereignty of God, and the redemptive plan for humanity. It serves as a powerful reminder of the challenges faced by early Christians and the universal relevance of their experiences. This verse continues to resonate with believers today, providing encouragement and strength in the face of opposition and adversity.