Romans 10:21 in the King James Version (KJV) of the Bible reads, "But to Israel he saith, All day long I have stretched forth my hands unto a disobedient and gainsaying people."

This verse comes at the end of a chapter in which the apostle Paul discusses the importance of faith in Christ for salvation. In the preceding verses, Paul explains that belief in Jesus as Lord and Savior is the only way to attain righteousness and salvation, and that this message is available to all people, both Jews and Gentiles. However, despite the availability of this message, Israel, as a nation, has rejected it. The verse concludes with a lament from God, expressing his sorrow at the disobedience of the Israelites.

The themes present in this verse include the persistent outreach of God, the disobedience of the Israelites, and the universality of God's message. This verse also touches on the overarching narrative of the Bible, which is the story of God's love for humanity, and his constant pursuit of a relationship with his creation, despite human disobedience and rejection.

The context of this verse is important to understanding its significance. In the broader context of the book of Romans, the apostle Paul is addressing the tension between Jews and Gentiles within the early Christian community. He is advocating for a message of inclusivity, in which all people, regardless of their heritage or background, are invited to receive the gift of salvation through faith in Christ.

The verse itself is a direct quotation from the Old Testament, specifically from the book of Isaiah. In Isaiah 65:2, the prophet writes, "I have spread out my hands all the day unto a rebellious people, which walketh in a way that was not good, after their own thoughts." This reference serves to link the message of the New Testament with the prophetic tradition of the Old Testament, reinforcing the continuity of God's message throughout history.

The symbolism in this verse lies in the imagery of God stretching out his hands to a disobedient people. This image conveys both the persistent outreach of God, as well as the rejection and disobedience of the Israelites. The act of stretching out one's hands is a gesture of invitation, of longing for a response, and is an expression of God's desire for relationship with his people.

The verse also highlights the concept of God's sovereignty and his foreknowledge. Despite knowing that the Israelites would reject him, God continues to reach out to them, demonstrating his unwavering love and grace. This serves as a reminder of God's enduring faithfulness, even in the face of human rebellion.

In summary, Romans 10:21 in the King James Version of the Bible conveys a message of God's persistent outreach to a disobedient people, as well as the universal availability of his message of salvation. It highlights the themes of faith, obedience, and God's unwavering love, and serves as a reminder of the continuity of God's message throughout history. Through its imagery and context, this verse offers a profound meditation on the nature of God's relationship with humanity and the persistent call to faith and obedience.